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Predictive model in transplantation

Monday September 23, 2024 - 13:40 to 15:10

Room: 3B-01 Room

249.6 Innovation in liver transplantation: Volume calculation using reality capture hardware via LIDAR 3D technology

Konstantina Eleni Karakasi, Greece

Department of Transplantation Surgery
Center for Research and Innovation in Solid Organ Transplantation
Aristotle University School of Medicine

Abstract

Innovation in liver transplantation: Volume calculation using reality capture hardware via LIDAR 3D technology

Konstantina Karakasi1, Georgios Katsanos1, Stavros Neiros1, Filippos F. Karageorgos1, Athanasios Kofinas1, Stella Vasileiadou1, Nikolaos Antoniadis1, Georgios Tsoulfas1.

1Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ , Transplantation, Aristotle University School of Medicine, Thessaloniki, Greece

Introduction: In various liver-related diseases, both liver resection and liver transplantation are considered to be potential treatments. The latter is the gold standard in end-stage liver disease. In both liver resection and liver transplantation, it is necessary to estimate liver volume accurately. The Light Detection And Ranging (LIDAR 3D) technology could assist. Here, the results of a LIDAR 3D camera usage on estimating liver volume are presented. Specifically, the total liver volume from 23 liver grafts and the total liver volume and left lobe from 9 cadaveric livers were examined.
Method: 23 hepatic grafts from brain-dead donors and 9 cadaveric livers were utilized. The following procedure was used for the 23 hepatic grafts. All demographic characteristics of hepatic graft donors were recorded (i.e., age, weight, height, and cause of brain death). A biopsy on all hepatic grafts was performed. The total volume of hepatic grafts suitable for transplantation was estimated. After the back-table preparation of the graft, the liver was weighed on a precision scale, and pictures were taken using a special LIDAR camera. The whole process lasted 2.5-3 min, and in all cases, the grafts were not left outside the preservation solution for long. 23 liver grafts were assessed from June 2021 to December 2022. The graft mass (g), the camera-estimated graft volume (mL), the graft volume estimated based on the Vauthey formula (mL), the transformation of the volume measured to estimated volume, and their difference in grams and percentile deviation were recorded in our database. For the 9 cadaveric livers, the following procedure was used. The liver was weighted, and its volume was measured using the water immersion technique. Afterward, a series of pictures were taken with a LIDAR camera to estimate the total liver volume and the left lobe volume. Then,actual left lobe was weighted, and the volume was measured using the water immersion technique. 
Results For the 23 liver grafts from brain-dead donors, a t-test of related samples was followed to calculate the p-value for statistically significant differences among samples. The mean total weight was 1521.2g,and the mean estimated weight was 1627.7g.The two groups had no statistically significant difference (P=0.314). For the 9 cadaveric livers the t-test was used to compare the actual and the estimated mass.The mean total mass was 1647.3g and the mean estimated mass was 1576.9 g. The two groups had no statistically significant difference (P=0.744). In addition, a t-test was used for the left lobe graft. The mean left lobe mass was 283.1 g, and the mean estimated mass was 264.3g. The two groups had no statistically significant difference (P=0.708) in a 95% confidence interval (-86,123).
Conclusion:  The results of the LIDAR 3D camera usage indicate a safe and viable option for estimating total liver volume for liver transplantation and left lobe liver volume for split liver transplantation.

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