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P.373 Analysis of the relationship between the MELD Scores and intraoperative LRRBC consumption in LDLT surgery at First Central Hospital of Mongolia

Odonchimeg Gombosuren, Mongolia

Anesthesiologist
Anesthesiology
First Central Hospital of Mongolia

Abstract

Analysis of the relationship between the MELD Scores and intraoperative LRRBC consumption in LDLT surgery at First Central Hospital of Mongolia

Bolormaa Lkhamsuren1, Bazarragchaa Regjii1, Odonchimeg Gombosuren1, Chuluunbaatar Donkhim1, Ganbold Lundeg2, Bayalagmaa Khuvtsagaan1.

1Organ transplantation center, First Central hospital of Mongolia, Ulaanbaatar, Mongolia; 2Anesthesia and intensive care department, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Introduction: Surgical procedures, operation time, and pre-existing impaired coagulation status promote massive bleeding, often leading to the excessive administration of red blood cells to restore oxygen delivery during liver transplantation surgery. Massive transfusion of blood products significantly increases post-transplantation morbidity and mortality. 
Objectives: We investigated the relationship between intraoperative LRRBC consumption during LDLT and the MELD scores of patients at the First Central Hospital of Mongolia, in 2023.
Methods: We selected a total of 50 liver recipients, who underwent LDLT surgery between Jan 5, to Dec 20, 2023, and were divided into three groups. Group 1 MELD≤10 (n=7), group 2 MELD=11-19 (n=33), and group 3 MELD=20-29 (n=10). In each selected group, the relationship between patients' MELD score and intraoperative LRRBC utilization was analyzed.
Results: In group 1 (MELD≤10) 0.69±0.84 liters, in group 2 (MELD=11-19) 2.09±2.25 liters, and in group 3 (MELD=20-29) 3.82±7.9 liters LRRBC was transfused during LDLT surgery. 
Conclusions: In this study, intraoperative leucocyte-reduced red blood cell consumption was analyzed high among patients who undergo living donor liver transplantation (LDLT) with a higher model for end-stage liver disease (MELD ≥20) score.

Abbreviation: LRRBC – leucocyte reduced red blood cell, LDLT – living donor liver transplantation, MELD – a model for end-stage liver disease
Keywords: Intraoperative, MELD score, leucocyte-reduced red blood cell

References:

[1] Intraoperative, MELD score, leucocyte-reduced red blood cell

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