Serum symphony: Harmonizing renal transplants in Argentina
Manuel Quirno Costa1, Lucas Monzón1.
1Laboratorio Nacional de Inmunogenética, INCUCAI, Buenos Aires, Argentina
Introduction: The Argentine kidney transplant waitlist faces challenges in serum availability and registration discrepancies. The study explores the vital role of the serum bank in donor matching and the efficiency of transplantation processes.
Methods: Utilizing data from the SINTRA database (January 23, 2024), the study focuses on kidney waitlist patients, analysing registration status and serum classification (non-expired, expired, or lacking sera).
Results: A critical issue arises with 878 "in-process" patients lacking official registration, particularly affecting hypersensitized and last vascular access individuals. Despite a dedicated serum bank, a concerning percentage of these patients lack essential serum, hindering compatible matches. Examination of 3926 patients reveals challenges of expired sera (n=985) and serum unavailability (n=542), impacting effective participation in transplants.
Discussion: Disparities in serum and registration status highlight the need for systemic improvements. Collaborative efforts and streamlined registration processes are proposed to address unregistered patients and enhance the system's efficiency. Regular serum updates are crucial for accurate crossmatch tests and successful transplantation. Challenges such as expired sera and serum unavailability emphasize the urgency for proactive measures.
Conclusion: The study underscores the pivotal role of a well-maintained serum bank in transplant success. Addressing challenges through proactive measures is key to ensuring timely serum availability, minimizing delays, and improving graft outcomes for patients awaiting renal transplantation in Argentina.