Professor of Surgery
Surgery
University of Maryland School of Medicine
Biography
Muhammad Mansoor Mohiuddin, MD/MBBS, DSc(Hon), FAST
Dr. Mohiuddin currently serves as a tenured Professor of Surgery and Director of the cardiac
xenotransplantation program at the University of Maryland School of Medicine (UMSOM),
Baltimore, MD. Dr Mohiuddin previously served as Chief of Transplantation of the
Cardiothoracic Surgery Research Program at the National Heart Lung and Blood Institute / the
National Institutes of Health (NIH). He held faculty positions at the University of Pennsylvania,
Philadelphia, and Rush University, Chicago.
He has been involved in Xenotransplantation Research since 1991 and started
xenotransplantation research programs at the NIH, Rush University Chicago, and at UMSOM..
He is Associate Editor for Transplantation and reviews manuscripts for many other journals. He
is also the past president Dow Graduate Association of North America. His achievements include
several NIH and non-NIH grants during his academic career. He is a member of the executive
committee of the Community of Transplant Scientists (COTS) and a member of the advisory
council of transplant regenerative medicine of the American Society of Transplantation (AST)
Dr. Mohiuddin's career has been a testament to his pioneering spirit in Xenotransplantation. His
groundbreaking contributions include demonstrating the most prolonged survival in heterotopic
and orthotopic cardiac Xenotransplantation. He devised an immunosuppression regimen that
significantly extended the lifespan of cardiac xenografts to nearly three years. His leadership
extends to the International Xenotransplantation Association (IXA), where he now serves as
President, following four years as Councilor and a liaison to foster productive dialogue between
the IXA and the FDA. His extensive publication record includes over 120 papers and more than
150 abstracts, and he has been a sought-after expert speaker on Xenotransplantation on numerous
occasions.
Dr. Mohiuddin's unwavering dedication to Xenotransplantation culminated in two significant
milestones. On January 7, 2022, he achieved the First Genetically Engineered pig-to-human
cardiac Xenotransplantation, a feat that marked a new era in the field. He then led the second
xenotransplantation procedure in September 2023, further solidifying his position as a leader in
the field. Both surgeries were successfully conducted at the University of Maryland Medical
Center in Baltimore, Maryland.
Besides other awards, Dr Mohiuddin was picked by Nature Journal as one of the “Nature’s 10”
in 2022. Ten people who helped shape science in 2022.