Aim: Coronary artery disease is highly prevalent in patients with end-stage renal disease and is the leading cause of death. In these patients, cardiovascular evaluation before kidney transplantation should be performed to detect coronary artery disease and determine perioperative cardiac risk, even if the patient is asymptomatic. The aim of this study was to evaluate the clinical value of Tc-99m MIBI gated myocardial perfusion scintigraphy (MPS) in the detection of coronary artery disease in patients with end-stage renal disease.
Material-method:  One hundred seventy- four patients with end-stage renal disease were included in the study (76 F, 98 M, mean age 49.14±24.81 years). Tc-99m MIBI stress and rest gated MPS was performed in all cases using SPECT camera. Perfusion and wall motion images of the left ventricle were evaluated visually by Nuclear Medicine physicians.  Coronary angiography (CAG) was subsequently performed in cases with findings suggestive of coronary artery disease in Tc-99m MIBI gated MPS.
Results:  Tc-99m MIBI gated MPS was normal in 157  of the patients.   Reversible perfusion defects and wall motion abnormalies were observed in 17 patients. These 17 patients then underwent CAG and the findings were determined to be compatible with the scintigraphy,  revascularization was performed.
Conclusion: It was thought that Tc-99m MIBI gated MPS could be a preferred method in the diagnosis of coronary artery disease before transplantation in patients with end-stage kidney disease, as it is noninvasive, easy to apply and has high diagnostic accuracy.