This workshop will focus on practical, ethical and legal complexities of seeking consent in the setting of deceased donation of organs and tissues for research and transplantation of deceased donor organs. Three talks will address common challenges such as the need to satisfy standards for valid consent while avoiding overburdening decision-makings with potentially unnecessary information due to periods of significant emotional stress or distress. Examples of approaches taken in different settings to manage the practicalities of consent will be explored and a panel discussion will examine key questions aimed at providing general guidance for how to manage ethical and practical dilemmas of consent in a range of contexts.