Introduction: Since 2014, transplant societies relied more on donor factors with the kidney donor profile index (KDPI) than traditional donor factors such as extended or standard kidney criteria. However, the strategies differ widely and the KDPI applicability remains to be validated in our region. We aim to evaluate the relationship between KDPI and transplant outcomes for donors after brain death (DBD).
Methods: We retrospectively analyzed the Kidney Donor Profile Index (KDPI) of 105 adult kidney transplant recipients at our centre using data from our electronic records and donor and recipients' files from the year 2005 to 2010 and followed them up to 12 years.
Results: In our cohort, 12 years of kidney allograft survival was 50% and KDPI did not affect death-censored graft survival. Female donors and donors with hypertension were significantly associated with poor graft survival. 12 years patients’ survival was around 75%. Again, the KDPI score showed no effect on patients’ survival. Young donors and donors with normal BMI had a significantly positive impact on patients’ survival. The hazard ratio of death was higher in recipients with old age and comorbidities like diabetes mellitus, hypertension, coronary artery disease, and cerebrovascular accidents.
Conclusion: We conclude that KDPI as a tool had no impact on our patients and graft survival. Our study had some limitations because of its retrospective nature, small numbers of deceased donors, and perhaps selection bias at the time of donors’ referral, however, our donors had KDPI scores ranging from low to very high in our study.